HRID2178723

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID16043572

3,3-Dimethyl-1-(trifluoromethyl)-1,3-dihydro-1lambda~3~,2-benziodoxole

C10H10F3IO

HCID24776901

4-(Benzyloxy)-1-methyl-1H-indole

C16H15NO

PRODUCTS

生成物

HCID68379783

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID69023

Acetic acid, copper(1+) salt

C2H3CuO2

PROCEDURE

实验过程

4-(Benzyloxy)-1-methyl-1H-indole and 3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole were treated with copper(I) acetate to give 4-(benzyloxy)-1-methyl-2-(trifluoromethyl)-1H-indole. Debenzylation via transfer hydrogenation with ammonium formate afforded 1-methyl-2-(trifluoromethyl)-1H-indol-4-ol.