Hydrochloric Acid → HCID 131724852, compound

HRID 2179917Notes

Reaction equation

HRID 2179917 reaction equation
[ClH:1].[O:2]([CH:10]1[CH:24]([N:25]([CH3:27])[CH3:26])[C:23]2=[CH:28][CH:20]([O:21][C:22]2=[O:29])[CH:19]2[CH:15]([O:16][C:17](=[O:31])[CH:18]2[CH3:30])[CH2:14][C:13]2([CH3:32])[CH:11]1[O:12]2)[Si:3]([C:6]([CH3:9])([CH3:8])[CH3:7])([CH3:5])[CH3:4]>CC(C)=O>[ClH:1].[Si:3]([O:2][CH:10]1[CH:24]([N:25]([CH3:27])[CH3:26])[C:23]2=[CH:28][CH:20]([O:21][C:22]2=[O:29])[CH:19]2[CH:15]([O:16][C:17](=[O:31])[CH:18]2[CH3:30])[CH2:14][C:13]2([CH3:32])[CH:11]1[O:12]2)([C:6]([CH3:9])([CH3:7])[CH3:8])([CH3:4])[CH3:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 85051032HCID 85051032, compound

Product 1

HCID 131724852HCID 131724852, compoundYield 65.2%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A solution of hydrochloric acid (0.3 mmol; 0.3 ml; 1N in ether) is added to a solution of the compound of Example 16 (0.22 mmol; 100 mg) in acetone (2 ml). The precipitate is filtered, washed with a little acetone, with ether and dried under reduced pressure. 70 mg of the expected product is obtained in the form of a white powder.

Workup

  1. filtrationThe precipitate is filtered
  2. washwashed with a little acetone, with ether
  3. customdried under reduced pressure

Sources & evidence

ORD record
ord-ed9fda5824734000861599dc9385680f
Source dataset
uspto-grants-2005_05
Patent number
US06887869B2

Reaction notes

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