Hydrochloric Acid → HCID 131724853, compound

HRID 2179918Notes

Reaction equation

HRID 2179918 reaction equation
[ClH:1].[S:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[C:7]([O:9][CH:10]1[CH:24]([N:25]([CH3:27])[CH3:26])[C:23]2=[CH:28][CH:20]([O:21][C:22]2=[O:29])[CH:19]2[CH:15]([O:16][C:17](=[O:31])[CH:18]2[CH3:30])[CH2:14][C:13]2([CH3:32])[CH:11]1[O:12]2)=[O:8]>CC(C)=O>[ClH:1].[S:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[C:7]([O:9][CH:10]1[CH:24]([N:25]([CH3:27])[CH3:26])[C:23]2=[CH:28][CH:20]([O:21][C:22]2=[O:29])[CH:19]2[CH:15]([O:16][C:17](=[O:31])[CH:18]2[CH3:30])[CH2:14][C:13]2([CH3:32])[CH:11]1[O:12]2)=[O:8]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 85336862HCID 85336862, compound

Product 1

HCID 131724853HCID 131724853, compoundYield 84.5%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A solution of hydrochloric acid (0.8 mmol; 0.8 ml; 1N in ether) is added to a solution of the compound of Example 29 (0.44 mmol; 196 mg) in acetone (4 ml). The precipitate is filtered, washed with a little acetone, with ether and dried under reduced pressure. 180 mg of the expected product is obtained in the form of a white powder.

Workup

  1. filtrationThe precipitate is filtered
  2. washwashed with a little acetone, with ether
  3. customdried under reduced pressure

Sources & evidence

ORD record
ord-3ac911f59f954970ad3ec37e4b448092
Source dataset
uspto-grants-2005_05
Patent number
US06887869B2

Reaction notes

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