反应详情

温度

50 °C

N-t-butoxycarbonyl-3,5-dimethoxy-4-(2,2,2-trifluoroethoxy)aniline (1.10 g, 3.13 mmol) was added to a 10% solution of hydrogen chloride in methanol (20 mL, 55 mmol), and the resulting solution was stirred at 50° C. for 30 minutes. The reaction mixture was concentrated under reduced pressure to give crude 3,5-dimethoxy-4-(2,2,2-trifluoroethoxy)aniline hydrochloride.

1. concentrationThe reaction mixture was concentrated under reduced pressure