反应详情

1,4-di(3,3,4,4,5,5,6,6,6-nonafluorohexyl) succinate (500 g, 0.82 mol), N,N-dimethylaminoethylamine (79.5 g, 0.90 mol) and potassium carbonate (11.3 g, 0.08 mol) were dissolved in acetonitrile (500 mL) and refluxed with heating for 45 minutes. Then, the reaction mixture was transferred to a separating funnel and added with ethyl acetate (2 L). The organic phase was washed with an aqueous solution of sodium chloride (1.5 L) and collected, and the organic solvent was evaporated under reduced pressure to obtain the target compound (453 g, yield: 79%) as light yellow oil.

1. temperaturerefluxed
2. temperaturewith heating for 45 minutes
3. customThen, the reaction mixture was transferred to a separating funnel
4. washThe organic phase was washed with an aqueous solution of sodium chloride (1.5 L)
5. customcollected
6. customthe organic solvent was evaporated under reduced pressure