反应详情

20 g (85.5 mmol) of the compound from example 26A are dissolved in 250 ml of anhydrous toluene and admixed with 22.4 g (85.5 mmol) of triphenylphosphine. The solution is heated under reflux for 16 h, in the course of which a precipitate separates out. The mixture is allowed to cool and the precipitate is filtered off. After washing with diethyl ether, it is dried under reduced pressure. This affords 39 g (92% of theory) of the desired product.

1. temperatureThe solution is heated
2. temperatureunder reflux for 16 h, in the course of which a precipitate
3. temperatureto cool
4. filtrationthe precipitate is filtered off
5. washAfter washing with diethyl ether, it
6. customis dried under reduced pressure