3-Fluorophenol → HCID 53661325, compound

HRID 2185639Notes

Reaction equation

HRID 2185639 reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][C:5](Cl)=[O:6].[F:8][C:9]1[CH:10]=[C:11]([OH:15])[CH:12]=[CH:13][CH:14]=1>>[F:8][C:9]1[CH:10]=[C:11]([O:15][C:5](=[O:6])[CH2:4][CH2:3][CH2:2][Cl:1])[CH:12]=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 97433-FluorophenolHCID 783704-Chlorobutyryl chloride

Product 1

HCID 53661325HCID 53661325, compound

Procedure

4-Chlorobutyrylchloride (35.3 g) was added to 3-fluorophenol (25 g). This mixture was stirred during 48 h at room temperature. After the reaction was completed the product was purified by vacuo-destillation. Yield: 35,3 g (b.p. 106° C. 3 mmHg) of 4-chloro-butanoic acid 3-fluorophenyl ester as a white oil.

Workup

  1. customwas purified by vacuo-destillation

Sources & evidence

ORD record
ord-0ef28005a6694d8da1899c0fe5492031
Source dataset
uspto-grants-2002_06
Patent number
US06403573B1

Reaction notes

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