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5.0 g (30.27 mmol) of L-phenylalanine are dissolved in 50 ml of concentrated hydrochloric acid and 4.0 g of para-formaldehyde and 1 ml of concentrated sulphuric acid are added. This solution is maintained at reflux for two days. After cooling and filtration, the resulting solid is dissolved in a 1/1 (v/v) hot water/ethanol mixture and aqueous NH4OH (30%) is added until a pH 7.0 is reached. The crystals which have precipitated after cooling the solution are recovered by filtration, washed with ethanol and dried. The desired product is thus obtained.

1. temperatureThis solution is maintained
2. temperatureat reflux for two days
3. temperatureAfter cooling
4. filtrationfiltration
5. dissolutionthe resulting solid is dissolved in a 1/1 (v/v) hot water/ethanol mixture and aqueous NH4OH (30%)
6. additionis added until a pH 7.0
7. customThe crystals which have precipitated
8. temperatureafter cooling the solution
9. filtrationare recovered by filtration
10. washwashed with ethanol
11. customdried