Oxalyl chloride → HCID 22452669, compound

HRID 2185899Notes

Reaction equation

HRID 2185899 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:15]([OH:17])=O)[C:6]2[CH2:7][CH2:8][CH2:9][CH2:10][C:11]=2[C:12]=1[O:13][CH3:14].C(Cl)(=O)C([Cl:21])=O>C(Cl)Cl.CN(C=O)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:15]([Cl:21])=[O:17])[C:6]2[CH2:7][CH2:8][CH2:9][CH2:10][C:11]=2[C:12]=1[O:13][CH3:14]

Participants

5

Reactant 2

HCID 65578Oxalyl chlorideHCID 22452660HCID 22452660, compound

Product 1

HCID 22452669HCID 22452669, compound

Reagents, catalysts & solvents 2

HCID 6228DimethylformamideCatalystHCID 6344DichloromethaneSolvent

Procedure

To a solution of 3,4-dimethoxy-5,6,7,8-tetrahydro-1-naphthalenecarboxylic acid (0.20 g, 0.85 mmol) in DCM (5 mL) was added oxalyl chloride (0.09 mL, 1.06 mmol) and 1 drop of DMF. The mixture was stirred at room temperature for 2 h. The solvent was removed in vacuo and the 3,4-dimethoxy-5,6,7,8-tetrahydro-1-naphthalenecarbonyl chloride was used without purification.

Workup

  1. customThe solvent was removed in vacuo
  2. customthe 3,4-dimethoxy-5,6,7,8-tetrahydro-1-naphthalenecarbonyl chloride was used without purification

Sources & evidence

ORD record
ord-bacb5c4148bc474ebb3a00f76261c2b4
Source dataset
uspto-grants-2002_06
Patent number
US06403601B1

Reaction notes

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