Hydrochloric Acid → 1-(3-Bromophenyl)-3-methyl-1H-pyrazole

HRID 2186209Notes

Reaction equation

HRID 2186209 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([NH:8][NH2:9])[CH:5]=[CH:6][CH:7]=1.Cl.[C:11]1(NN)[CH:16]=CC=[CH:13][CH:12]=1>>[Br:1][C:2]1[CH:3]=[C:4]([N:8]2[CH:16]=[CH:11][C:12]([CH3:13])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 7516PhenylhydrazineHCID 33758(3-Bromophenyl)hydrazine

Product 1

HCID 179399391-(3-Bromophenyl)-3-methyl-1H-pyrazole

Procedure

This compound was prepared by the same methodology described for EXAMPLE 1 with 3-bromophenyl hydrazine.HCl substituted for phenyl hydrazine. There was obtained 1-(3-bromophenyl)-3-methyl-1H-pyrazole-5-[(2′-aminosulfonyl-[1,1′]-biphen-4-yl)carboxyamide; HRMS(M+H)+ calc. 511.043949; found: 511.043295.

Workup

  1. customThis compound was prepared by the same methodology

Sources & evidence

ORD record
ord-6c42dc5821314aab9a457d7ce9d338ad
Source dataset
uspto-grants-2002_06
Patent number
US06403620B1

Reaction notes

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