Hydrochloric Acid → 1-(4-Chlorophenyl)-3-methyl-1H-pyrazole

HRID 2186210Notes

Reaction equation

HRID 2186210 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][NH2:9])=[CH:4][CH:3]=1.Cl.[C:11]1(NN)[CH:16]=CC=[CH:13][CH:12]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:16]=[CH:11][C:12]([CH3:13])=[N:9]2)=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 7516PhenylhydrazineHCID 70624(4-Chlorophenyl)hydrazine

Product 1

HCID 179399681-(4-Chlorophenyl)-3-methyl-1H-pyrazole

Procedure

This compound was prepared by the same methodology described for EXAMPLE 8 with 4-chlorophenyl hydrazine.HCl substituted for phenyl hydrazine and 2-amino-5-(2-N-t-butylaminosulfonylphenyl)pyridine was used in the coupling step. There was obtained the title compound; HRMS (M+H)+: calc. 468.089714; found 468.088873.

Workup

  1. customThis compound was prepared by the same methodology

Sources & evidence

ORD record
ord-3e6cac7adaf14a039318a865c2735d71
Source dataset
uspto-grants-2002_06
Patent number
US06403620B1

Reaction notes

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