Potassium Carbonate → HCID 9799231, compound

HRID 2186808Notes

Reaction equation

HRID 2186808 reaction equation
C([NH:4][C:5]1[S:6][C:7]2[CH:13]=[C:12]([C:14](=[O:17])[CH2:15]Br)[CH:11]=[CH:10][C:8]=2[N:9]=1)(=O)C.[CH2:18]([CH:25]1[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.C([O-])([O-])=O.[K+].[K+]>CN(C=O)C>[NH2:4][C:5]1[S:6][C:7]2[CH:13]=[C:12]([C:14](=[O:17])[CH2:15][N:28]3[CH2:29][CH2:30][CH:25]([CH2:18][C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=4)[CH2:26][CH2:27]3)[CH:11]=[CH:10][C:8]=2[N:9]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 317384-BenzylpiperidineHCID 22449940HCID 22449940, compound

Product 1

HCID 9799231HCID 9799231, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 2 g of 1-(2-Acetylamino-benzothiazol-6-yl)-2-bromo-ethanone and 1.5 g of 4-benzylpiperidin and 2.5 g of K2CO3 in 20 ml of DMF was heated at 35° C. for 2 hours.

Sources & evidence

ORD record
ord-003341d922a74906bfdca559bbcb9e19
Source dataset
uspto-grants-2002_06
Patent number
US06407122B1

Reaction notes

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