反应详情

温度

80 °C

A mixture of 10.0 g (47 mmol) 4-methylphenacyl bromide, 6.8 g (47 mmol) 4-chlorothiophenol, and 6.5 g (47 mmol) anhydrous potassium carbonate in 100 ml dry DMF was stirred for 3 h at 80° C. It was filtered and the filtrate was concentrated under reduced pressure. The concentrate was stirred in water, and the resulting solid was filtered off, washed with water, and recrystallized from ethanol to give 10.7 g (82%) of the crude title compound.

1. filtrationIt was filtered
2. concentrationthe filtrate was concentrated under reduced pressure
3. stirringThe concentrate was stirred in water
4. filtrationthe resulting solid was filtered off
5. washwashed with water
6. customrecrystallized from ethanol