反应详情

温度

95 °C

4-Fluorobenzene-1,2-diamine (10.0 g, 0.077 mol) and potassium O-ethyl carbonodithioate (37.1 g, 0.234 mol) were dissolved in dry DMF (150 mL) under nitrogen and heated to 95° C. for 12 h. The reaction was cooled to RT and 200 mL water was added followed by addition of 5N HCl to get precipitates. After stirring for 1 h, the precipitates were collected by filtration, washed with water and dried under vacuum for 2 h. The crude compound was then washed with chloroform and dried to give 6-fluorobenzo[d]thiazole-2-thiol as yellow solid.

1. temperatureThe reaction was cooled to RT
2. customto get
3. customprecipitates
4. filtrationthe precipitates were collected by filtration
5. washwashed with water
6. customdried under vacuum for 2 h
7. washThe crude compound was then washed with chloroform
8. customdried