反应详情

温度

80 °C

In a glass tube, 250 mg of 1-(benzofuran-3-yl)-2-bromoethanone, 181 mg of 5-bromopyridin-2-ylamine and 105 mg of sodium hydrogencarbonate are dissolved in 15 ml of n-propanol. The tube is closed and heated at 80° C. for 20 h. After cooling, 20 ml of water are added and the reaction mixture is stirred for 1 hour at ambient temperature. A precipitate forms, and is recovered by filtration, washed with water and then with diisopropyl ether, and dried in a desiccator under reduced pressure. 250 mg of compound are obtained.

1. customThe tube is closed
2. temperatureAfter cooling
3. filtrationA precipitate forms, and is recovered by filtration
4. washwashed with water
5. dry with materialwith diisopropyl ether, and dried in a desiccator under reduced pressure