Hydrochloric Acid → HCID 86738632, compound

HRID 2198785Notes

Reaction equation

HRID 2198785 reaction equation
[ClH:1].[CH3:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][C:11]2([CH2:16][N:17]3[CH:21]=[CH:20][N:19]=[CH:18]3)[S:15][CH2:14][CH2:13][S:12]2)=[CH:5][CH:4]=1>>[ClH:1].[CH3:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:9][CH2:10][C:11]2([CH2:16][N:17]3[CH:21]=[CH:20][N:19]=[CH:18]3)[S:15][CH2:14][CH2:13][S:12]2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 13084412HCID 13084412, compound

Product 1

HCID 86738632HCID 86738632, compound

Procedure

Ethereal hydrogen chloride was added dropwise to a stirred solution of 2.0 g. of 1-[[2-(2-(4-methylphenyl)ethyl)-1,3-dithiolan-2-yl]methyl]imidazole in 30 ml. of anhydrous ether until precipitation was complete. The product was filtered off, washed with ether, air-dried and recrystallized from methanol/ethyl acetate to yield 1-[[2-(2-(4-methylphenyl)ethyl)-1,3-dithiolan-2-yl]methyl]imidazole hydrochloride--m.p. 206.5°-208° C.

Workup

  1. customof anhydrous ether until precipitation
  2. filtrationThe product was filtered off
  3. washwashed with ether
  4. customair-dried
  5. customrecrystallized from methanol/ethyl acetate

Sources & evidence

ORD record
ord-861365d9b521485fb1cd0c6e006cb281
Source dataset
uspto-grants-1982_11
Patent number
US04359475

Reaction notes

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