Hydroxyamine hydrochloride → HCID 13051039, compound

HRID 2198876Notes

Reaction equation

HRID 2198876 reaction equation
C(O)(=O)C.[OH:5][C:6]1[CH:19]=[C:18]2[C:9]([CH:10]=[CH:11][C:12]3[O:13][CH:14]=[C:15]([CH:21]=O)[C:16](=[O:20])[C:17]=32)=[CH:8][CH:7]=1.Cl.[NH2:24]O.C([O-])=O.[Na+]>C(O)=O>[OH:5][C:6]1[CH:19]=[C:18]2[C:9]([CH:10]=[CH:11][C:12]3[O:13][CH:14]=[C:15]([C:21]#[N:24])[C:16](=[O:20])[C:17]=32)=[CH:8][CH:7]=1

Participants

5

Reactant 3

HCID 443297Hydroxyamine hydrochlorideHCID 2723810Sodium FormateHCID 867372399-hydroxy-1-oxo-1H-naphtho[2,1-b]pyran-2-carboxaldehyde acetate

Product 1

HCID 13051039HCID 13051039, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

A mixture of compound 5, hydroxylamine hydrochloride and sodium formate is refluxed in formic acid to provide 9-hydroxy-1-oxo-1H-naphtho[2,1-b]pyran-2-carbonitrile, Compound 8.

Sources & evidence

ORD record
ord-0e7f72d2dc464ab9bfbb6bdb27835ab3
Source dataset
uspto-grants-1982_11
Patent number
US04360527

Reaction notes

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