反应详情

A 0.23 g. amount of sodium metal is dissolved in 75.0 ml. of absolute ethanol, then 10.8 g. of phenylhydrazine is added, followed in 5 minutes by 3.6 g. of α-methylcrotononitrile. The reaction mixture is refluxed for 18 hours, then is evaporated to dryness in vacuo. Water is added to give a gum which solidifies on standing for 16 hours. The solid is collected and dissolved in dichloromethane. The procedure of Example 15 is continued to give 1.6 g. of the desired product as light yellow crystals, m.p. 123°-125° C.

1. temperatureThe reaction mixture is refluxed for 18 hours
2. customis evaporated to dryness in vacuo
3. additionWater is added
4. customto give a gum which
5. waiton standing for 16 hours
6. customThe solid is collected
7. dissolutiondissolved in dichloromethane
8. customto give 1.6 g