反应详情

温度

80 °C

To a mixture of EXAMPLE 402A (2.3 g) in acetic acid (40 ml) was added concentrated hydrochloric acid (3 ml). The mixture was heated at 80° C. for 4 hours. After cooling to room temperature, precipitation of the product occurred. Water (50 mL) was added to further induce precipitation. The solid was filtered, rinsed with water and dried in vacuo.

1. temperatureAfter cooling to room temperature
2. customprecipitation of the product
3. additionWater (50 mL) was added to further induce precipitation
4. filtrationThe solid was filtered
5. washrinsed with water
6. customdried in vacuo