Hydrazine hydrate (1:1) → HCID 178487565, compound

HRID 2199990Notes

Reaction equation

HRID 2199990 reaction equation
F[C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[C:10](=O)[CH3:11].O.[NH2:14][NH2:15]>>[CH3:9][O:8][C:6]1[CH:7]=[C:2]2[C:3]([C:10]([CH3:11])=[N:14][NH:15]2)=[CH:4][CH:5]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 5928212'-Fluoro-4'-methoxyacetophenone

Product 1

HCID 178487565HCID 178487565, compound

Conditions

Temperature
140 °C

Procedure

To 2′-fluoro-4′-methoxyacetophenone (5.24 g) was added hydrazine monohydrate (20 mL) at room temperature, and then the reaction mixture was stirred at 140° C. for 20 hours. The precipitated solid was filtered to give the titled compound (4.20 g) as a red solid.

Workup

  1. filtrationThe precipitated solid was filtered

Sources & evidence

ORD record
ord-8640430c58224d3599a5cb7d605701ef
Source dataset
uspto-grants-2016_06
Patent number
US09359350B2

Reaction notes

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