Diethylamine → HCID 15064526, compound

HRID 2201615Notes

Reaction equation

[NH:1]([CH2:4][CH3:5])[CH2:2][CH3:3].[Br:6][C:7]([F:14])([F:13])[C:8]([O:10]CC)=O>>[Br:6][C:7]([F:13])([F:14])[C:8]([N:1]([CH2:4][CH3:5])[CH2:2][CH3:3])=[O:10]

Participants

Reactant 2

HCID 8021Diethylamine

HCID 69585Ethyl bromodifluoroacetate

Product 1

HCID 15064526HCID 15064526, compound

Procedure

Et2NH (7.9 g, 108 mmol) was added to ethyl bromodifluoroacetate (20.1 g, 99 mmol) at 30° C. The mixture was stirred for 60 min; then all volatiles were removed under reduced pressure. To the residue was added another 7.9 g of Et2NH and the mixture was stirred another 60 min.

Workup

customthen all volatiles were removed under reduced pressure
additionTo the residue was added another 7.9 g of Et2NH
stirringthe mixture was stirred another 60 min.

Sources & evidence

ORD record: ord-c4c3c09fe5dd4afe88b184f3905ccc2e
Source dataset: uspto-grants-2016_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09365495B2

Reaction notes

Loading…