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HRID2204871

反应详情

EQUATION

反应方程式

HRID 2204871 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)N=C=S
HCID128851

Acetyl isothiocyanate

C3H3NOS

结构：CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)NN)n2)cc1
HCID59471632

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)NC(=S)NNC(=O)c1nc(-c2ccc(S(=O)(=O)C(C)C)cc2)cnc1N
HCID59471667

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCCl
溶剂HCID11

1,2-Dichloroethane

C2H4Cl2

PROCEDURE

实验过程

A mixture of 3-amino-6-(4-isopropylsulfonylphenyl)pyrazine-2-carbohydrazide (100 mg, 0.2982 mmol), acetyl isothiocyanate (30.16 mg, 26.20 μL, 0.2982 mmol) and dry DCE (2.000 mL) were stirred at ambient temperature for 2 h and then concentrated in vacuo. Used directly in the next step without further purification; MS (ES+) 437.20

WORKUP

后处理

  1. concentrationconcentrated in vacuo
  2. customUsed directly in the next step without further purification