4-Amino-3-pyridinesulfonamide → HCID 19378736, compound

HRID 2210446Notes

Reaction equation

HRID 2210446 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[S:8]([NH2:11])(=[O:10])=[O:9]>C(OC(=O)CCC)(=O)CCC>[OH2:9].[CH2:2]([C:7]1[NH:1][C:2]2[CH:7]=[CH:6][N:5]=[CH:4][C:3]=2[S:8](=[O:10])(=[O:9])[N:11]=1)[CH2:3][CH3:4]

Participants

3

Reactant 1

HCID 109759664-Amino-3-pyridinesulfonamide

Product 1

HCID 19378736HCID 19378736, compound

Reagents, catalysts & solvents 1

HCID 7798Butyric anhydrideSolvent

Conditions

Temperature
180 °C

Procedure

A mixture of 1 g of 4-aminopyridine-3-sulfonamide (Preparation 2) and 10 cm3 of butyric anhydride is heated to 180° C. for 18 hours. After cooling, the crystals obtained are collected on a filter, washed with a small amount of butyric anhydride and with diethyl ether and then dried. The product is recrystallized from hot water.

Workup

  1. temperatureAfter cooling
  2. customthe crystals obtained
  3. customare collected on a filter
  4. washwashed with a small amount of butyric anhydride and with diethyl ether
  5. customdried
  6. customThe product is recrystallized from hot water

Sources & evidence

ORD record
ord-ab5a45239e944353a2a59d3ef0c2f8a2
Source dataset
uspto-grants-1995_10
Patent number
US05459138

Reaction notes

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