2-Phenylethanol → HCID 19379177, compound

HRID 2210589Notes

Reaction equation

HRID 2210589 reaction equation
[OH:1][C:2]1[C:7]([C:8]([CH3:11])([CH3:10])[CH3:9])=[CH:6][C:5]([CH2:12][CH2:13][C:14]([OH:16])=[O:15])=[CH:4][C:3]=1[C:17]([CH3:20])([CH3:19])[CH3:18].[C:21]1([CH2:27][CH2:28]O)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1.C1(C)C=CC(S(O)(=O)=O)=CC=1>C1(C)C=CC=CC=1>[C:21]1([CH2:27][CH2:28][O:15][C:14](=[O:16])[CH2:13][CH2:12][C:5]2[CH:4]=[C:3]([C:17]([CH3:20])([CH3:19])[CH3:18])[C:2]([OH:1])=[C:7]([C:8]([CH3:11])([CH3:10])[CH3:9])[CH:6]=2)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Participants

5

Reactant 3

HCID 60542-PhenylethanolHCID 6101p-Toluenesulfonic acidHCID 883893-(3',5'-Di-tert-butyl-4'-hydroxyphenyl)propionic acid

Product 1

HCID 19379177HCID 19379177, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

3-(4-hydroxy-3,5-di-tert.-butylphenyl)-propionic acid-2-phenylethyl ester was prepared from 278 g (1 mol) of 3-(4-hydroxy-3,5-di-tert.-butylphenyl)-propionic acid and 122 g (1 mol) of 2-phenylethanol by azeotropic esterification in toluene with 0.5 g of 4-toluenesulfonic acid. The product was analyzed and the results of this analysis were as follows:

Workup

  1. customthe results of this analysis

Sources & evidence

ORD record
ord-66892d50851c46f0986c4b910f3b5302
Source dataset
uspto-grants-1995_10
Patent number
US05459171

Reaction notes

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