Sodium Bicarbonate → HCID 13391750, compound

HRID 2210754Notes

Reaction equation

HRID 2210754 reaction equation
C1(C)C=CC(S(O)(=O)=O)=CC=1.[NH2:12][C@@H:13]1[C:35](=[O:36])[N:15]2[C:16]([C:23]([O:25][CH:26]([O:28][C:29]([O:31][CH:32]([CH3:34])[CH3:33])=[O:30])[CH3:27])=[O:24])=[C:17]([CH2:20][O:21][CH3:22])[CH2:18][S:19][C@H:14]12.C([O-])(O)=O.[Na+]>C(OCC)(=O)C>[NH2:12][C@@H:13]1[C:35](=[O:36])[N:15]2[C:16]([C:23]([O:25][CH:26]([O:28][C:29]([O:31][CH:32]([CH3:33])[CH3:34])=[O:30])[CH3:27])=[O:24])=[C:17]([CH2:20][O:21][CH3:22])[CH2:18][S:19][C@H:14]12

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 131719151HCID 131719151, compound

Product 1

HCID 13391750HCID 13391750, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

2.53 g (4.6 mmol) of diastereomer mixture from Example 1 were taken up in a mixture of ethyl acetate and 5% strength aq. NaHCO3 solution and stirred for 5 min. The phases were separated, and the organic phase was washed with satd. aq. NaCl solution, dried with MgSO4 and concentrated in vacuo.

Workup

  1. customThe phases were separated
  2. washthe organic phase was washed with satd
  3. dry with materialaq. NaCl solution, dried with MgSO4
  4. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-79edbeb7c9d5425eacf12fdcfa8b0d00
Source dataset
uspto-grants-1995_10
Patent number
US05461043

Reaction notes

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