Diisopropyl Ether → HCID 10686342, compound

HRID 2210890Notes

Reaction equation

HRID 2210890 reaction equation
[Cl:1][C:2]([Cl:17])([Cl:16])[C:3]([NH:5][C:6]1[CH:7]=[N:8][C:9]2[CH2:10][CH2:11][CH2:12][CH2:13][C:14]=2[CH:15]=1)=[O:4].ClC1C=CC=C(C(OO)=[O:26])C=1.C(OC(C)C)(C)C>C(Cl)Cl>[Cl:17][C:2]([Cl:1])([Cl:16])[C:3]([NH:5][C:6]1[CH:7]=[N+:8]([O-:26])[C:9]2[CH2:10][CH2:11][CH2:12][CH2:13][C:14]=2[CH:15]=1)=[O:4]

Participants

5

Reactant 3

HCID 7914Diisopropyl EtherHCID 70297m-Chloroperbenzoic acidHCID 10685153HCID 10685153, compound

Product 1

HCID 10686342HCID 10686342, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 24.03 g of Compound 2 obtained in the above step (2) in 40 ml of methylene chloride is added 21.2 g of 80% m-chloroperbenzoic acid at room temperature, and the resultant mixture is stirred for 45 minutes. The reaction mixture is mixed with isopropyl ether and the crystals are filtered to give 25.06 g of the titled compound 3 as crystals. Yield: 99% mp.: 244° to 246° C. (dec.)

Workup

  1. filtrationthe crystals are filtered

Sources & evidence

ORD record
ord-46a706550fbf4844aae3a66c868e4973
Source dataset
uspto-grants-1995_10
Patent number
US05461062

Reaction notes

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