Hydrochloric Acid → HCID 21962109, compound

HRID 2211837Notes

Reaction equation

HRID 2211837 reaction equation
[CH2:1]([CH:8]1[C:14](=[O:15])[N:13]([CH3:16])[CH2:12][CH2:11][CH2:10][N:9]1C(OC(C)(C)C)=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:24]>O1CCOCC1>[ClH:24].[CH2:1]([CH:8]1[NH:9][CH2:10][CH2:11][CH2:12][N:13]([CH3:16])[C:14]1=[O:15])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21962081HCID 21962081, compound

Product 1

HCID 21962109HCID 21962109, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

tert-Butyl 2-benzylhexahydro-4-methyl-3-oxo-1H-1,4-diazepine-1-carboxylate obtained in Step A was dissolved in 4M hydrochoride in dioxane and evaporated after 2.5 h to yield the hydrochloride salt of the desired compound.

Workup

  1. customevaporated after 2.5 h

Sources & evidence

ORD record
ord-37e9b7df95554d5ab1c4e6799e0842b4
Source dataset
uspto-grants-2006_09
Patent number
US07101871B2

Reaction notes

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