Iodoethane → N-[4-(2-Chloro-ethyl)-2-methyl-phenyl]-N-ethyl-acetamide

HRID 2211914Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2211914
[Cl:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11](=[O:13])[CH3:12])=[C:6]([CH3:14])[CH:5]=1.[CH2:15](I)[CH3:16]>>[Cl:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([N:10]([CH2:15][CH3:16])[C:11](=[O:13])[CH3:12])=[C:6]([CH3:14])[CH:5]=1

Komponenten

3

Edukt 2

HCID 6340IodoethaneHCID 21963464N-[4-(2-Chloro-ethyl)-2-methyl-phenyl]-acetamide

Produkt 1

HCID 21963286N-[4-(2-Chloro-ethyl)-2-methyl-phenyl]-N-ethyl-acetamideAusbeute 88 %

Versuchsvorschrift

N-[4-(2-Chloro-ethyl)-2-methyl-phenyl]-N-ethyl-acetamide was prepared according to the general method as outlined in Preparation 43 starting from N-[4-(2-chloro-ethyl)-2-methyl-phenyl]-acetamide (0.40 g, 1.89 mmol) and ethyliodide (0.189 mL, 2.36 mmol). After chromatographic purification, the product was isolated as a viscous oil (0.399 g, 1.66 mmol).

Aufarbeitung

  1. customAfter chromatographic purification

Quellen und Nachweise

ORD-Eintrag
ord-61552842dc6841bd88d5f08d25dfbdea
Quelldatensatz
uspto-grants-2006_09
Patentnummer
US07101886B2

Notizen zur Reaktion

Wird geladen…