反应详情

温度

50 °C

At room temperature, 144 g (0.576 mol) of 2-chloro-4-methyl-1,3-thiazole-5-sulphonamide are initially charged in 600 ml of acetonitrile, and 147 g (1.9 mol) of a 40% strength aqueous methylamine solution are metered in at room temperature. The reaction mixture is stirred at 50° C. for 6 h and then concentrated using a rotary evaporator. The residue is admixed with water, filtered off with suction and dried.

1. customare metered in at room temperature
2. concentrationconcentrated
3. customa rotary evaporator
4. filtrationfiltered off with suction
5. customdried