Hydrochloric Acid → HCID 21948303, compound

HRID 2214828Notes

Reaction equation

HRID 2214828 reaction equation
[CH2:1]([O:3][C:4]([NH:6][C:7]1([CH2:20][N:21]2[CH2:26][CH2:25][N:24]([S:27]([C:30]3[CH:35]=[CH:34][C:33]([CH:36]=[CH2:37])=[CH:32][CH:31]=3)(=[O:29])=[O:28])[CH2:23][C:22]2=[O:38])[CH2:12][CH2:11][N:10]([C:13]2[CH:18]=[CH:17][N:16]=[C:15]([CH3:19])[CH:14]=2)[CH2:9][CH2:8]1)=[O:5])[CH3:2].[ClH:39]>C(OCC)(=O)C>[ClH:39].[CH2:1]([O:3][C:4]([NH:6][C:7]1([CH2:20][N:21]2[CH2:26][CH2:25][N:24]([S:27]([C:30]3[CH:35]=[CH:34][C:33]([CH:36]=[CH2:37])=[CH:32][CH:31]=3)(=[O:28])=[O:29])[CH2:23][C:22]2=[O:38])[CH2:8][CH2:9][N:10]([C:13]2[CH:18]=[CH:17][N:16]=[C:15]([CH3:19])[CH:14]=2)[CH2:11][CH2:12]1)=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 101436531-{[4-Ethoxycarbonylamino-1-(2-methyl-4-pyridyl)-4-piperidinyl]methyl}-4-(4-vinylbenzenesulfonyl)-2-piperazinone

Product 1

HCID 21948303HCID 21948303, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

1-{[4-Ethoxycarbonylamino-1-(2-methyl-4-pyridyl)-4-piperidinyl]methyl}-4-(4-vinylbenzenesulfonyl)-2-piperazinone (86 mg) was suspended in ethyl acetate (10 ml), a 4N hydrochloric acid solution in ethyl acetate (0.3 ml) was added, and the resulting crystals were filtered off to obtain the title compound (38 mg) as colorless powders.

Workup

  1. filtrationthe resulting crystals were filtered off

Sources & evidence

ORD record
ord-9087d6bca24748aa8c9c1cdea4c50c99
Source dataset
uspto-grants-2006_09
Patent number
US07109200B2

Reaction notes

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