Propylamine → HCID 21943416, compound

HRID 2216538Notes

Reaction equation

HRID 2216538 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([CH:6]2[O:8][CH2:7]2)=[CH:4][CH:3]=1.[CH2:11]([NH2:14])[CH2:12][CH3:13]>>[CH2:11]([NH:14][CH2:7][CH:6]([OH:8])[C:5]1[CH:9]=[CH:10][C:2]([CH3:1])=[CH:3][CH:4]=1)[CH2:12][CH3:13]

Participants

3

Reactant 2

HCID 7852PropylamineHCID 1081112-(4-Methylphenyl)oxirane

Product 1

HCID 21943416HCID 21943416, compoundYield 49.6%

Procedure

4-Methyl styrene oxide(1.0 g,8.0 mmol)and 3 ml of propylamine in methanolic solution were charged into a flask. The flask was sealed and put in a refrigerator for 5–7 days. The solution was concentrated and the residue crystallized from ether, the title compound was obtained as white needle crystals, mp. 73.0–75.1 C, yield 49.6%.

Workup

  1. customThe flask was sealed
  2. waitput in a refrigerator for 5–7 days
  3. concentrationThe solution was concentrated
  4. customthe residue crystallized from ether

Sources & evidence

ORD record
ord-413e87f8e5924ce0a49c00cc5b24664d
Source dataset
uspto-grants-2006_09
Patent number
US07112605B2

Reaction notes

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