2-Bromopyridine → HCID 59652040, compound

HRID 221823Notes

Reaction equation

HRID 221823 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([CH3:15])=[N:13][NH:12][C:11](=[O:16])[CH:10]=2)=[CH:5][CH:4]=1.Br[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=1>[Cu](I)I>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([CH3:15])=[N:13][N:12]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=3)[C:11](=[O:16])[CH:10]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 79732-BromopyridineHCID 10775091HCID 10775091, compound

Product 1

HCID 59652040HCID 59652040, compound

Reagents, catalysts & solvents 1

HCID 83717Copper iodideCatalyst

Procedure

5-(4-Methoxy-phenyl)-6-methyl-2-pyridin-2-yl-2H-pyridazin-3-one was prepared from 5-(4-methoxy-phenyl)-6-methyl-2H-pyridazin-3-one and 2-bromopyridine in the presence of copper iodide using the procedure described in Example 98 Step 2; Mp 156-7° C.; MS m/z 294 (M+H).

Sources & evidence

ORD record
ord-5fb8d7df4a464a88a566313acc765955
Source dataset
uspto-grants-2012_06
Patent number
US08207168B2

Reaction notes

Loading…