反应详情

温度

170 °C

The title compound was prepared according to the procedure given for Example 9 using N-(4-(difluoromethoxy)phenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-amine (0.091 g, 0.31 mmol), 2,3-dichloropyridine (0.092 g, 0.62 mmol) and N,N-diisopropylethylamine (0.081 mL, 0.47 mmol) and heating the reaction mixture for 10 h at 170° C. to obtain 0.038 g of a light yellow solid.