Hydrochloric Acid → 4-(3-Methanesulfonyl-phenyl)-1-ethyl-piperidine

HRID 2220079Notes

Reaction equation

HRID 2220079 reaction equation
[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([CH:11]2[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]2)[CH:8]=[CH:9][CH:10]=1)(=[O:4])=[O:3].I[CH2:18][CH3:19].Cl>>[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([CH:11]2[CH2:16][CH2:15][N:14]([CH2:18][CH3:19])[CH2:13][CH2:12]2)[CH:8]=[CH:9][CH:10]=1)(=[O:4])=[O:3]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 6340IodoethaneHCID 129889574-(3-(Methylsulfonyl)phenyl)piperidine

Product 1

HCID 223978324-(3-Methanesulfonyl-phenyl)-1-ethyl-piperidine

Procedure

Beginning with 4-(3-methanesulfonyl-phenyl)piperidine and iodoethane: m.p. 158° C. (HCl). MS m/z (rel. intensity, 70 eV) 267 (M+, 20), 252 (bp), 130 (10), 115 (12), 84 (20);

Sources & evidence

ORD record
ord-6ed33c0e5bc8481a80f0ba5e557e5a3f
Source dataset
uspto-grants-2008_08
Patent number
US07417043B2

Reaction notes

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