Diethylamine → (2-Bromo-benzyl)-diethyl-amine

HRID 2220212Notes

Reaction equation

HRID 2220212 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8]Br.[CH2:10]([NH:12][CH2:13][CH3:14])[CH3:11]>C1(C)C=CC=CC=1>[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][N:12]([CH2:13][CH3:14])[CH2:10][CH3:11]

Participants

4

Reactant 2

HCID 8021DiethylamineHCID 769652-Bromobenzyl bromide

Product 1

HCID 10083076(2-Bromo-benzyl)-diethyl-amine

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To 1-Bromo-2-bromomethyl-benzene (2.17 g, 0.008 mmol) in toluene (15 mL) was added diethylamine (3.05 mL) and the mixture was stirred at room temperature for 14 hours. The reaction mixture was filtered and concentrated to give Example 229A as an oil.

Workup

  1. filtrationThe reaction mixture was filtered
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-ca758fde160a49c097dfedcef981117c
Source dataset
uspto-grants-2008_08
Patent number
US07417040B2

Reaction notes

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