Hydrochloric Acid → HCID 23134374, compound

HRID 2220622Notes

Reaction equation

HRID 2220622 reaction equation
O.[OH-].[Li+].C([O:6][C:7]([C:9]1[CH:14]=[C:13]([CH3:15])[C:12]([B:16]([OH:18])[OH:17])=[C:11]([CH3:19])[CH:10]=1)=[O:8])C.O.Cl>O1CCOCC1>[C:7]([C:9]1[CH:10]=[C:11]([CH3:19])[C:12]([B:16]([OH:17])[OH:18])=[C:13]([CH3:15])[CH:14]=1)([OH:8])=[O:6]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 168937Lithium hydroxide, monohydrateHCID 23134154HCID 23134154, compound

Product 1

HCID 23134374HCID 23134374, compoundYield 56%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Lithium hydroxide monohydrate (0.089 g) was added to a mixture of 4-ethoxycarbonyl-2,6-dimethylphenylboronic acid (0.047 g), water (1 mL) and 1,4-dioxane (1 mL), and the mixture was stirred at room temperature overnight. To the reaction mixture was added 2 mol/L hydrochloric acid (1.5 mL), and the solvent was evaporated under reduced pressure. The residue was washed with water to afford the title compound (0.023 g).

Workup

  1. customthe solvent was evaporated under reduced pressure
  2. washThe residue was washed with water

Sources & evidence

ORD record
ord-b6f74b46f5e447289f4f26acf9b054d8
Source dataset
uspto-grants-2008_08
Patent number
US07417169B2

Reaction notes

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