反应详情

To a mixture of lithium aluminum hydride (1.74 g) and tetrahydrofuran (100 mL) was added 1-ethyl-1H-imidazole-4-carbaldehyde (5.71 g) at 0° C. After stirring the reaction mixture for 1 hr, sodium sulfate decahydrate (15 g) was added and the mixture was further stirred at room temperature for 5 hrs. Insoluble materials were filtered off and the filtrate was concentrated to give (1-ethyl-1H-imidazol-4-yl)methanol as a colorless oil (5.83 g, yield 100%).

1. stirringthe mixture was further stirred at room temperature for 5 hrs
2. filtrationInsoluble materials were filtered off
3. concentrationthe filtrate was concentrated