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HRID2222165

反应详情

EQUATION

反应方程式

HRID 2222165 的结构方程式

REACTANTS

反应物

3
结构：C1CCNC1
HCID31268

Pyrrolidine

C4H9N

结构：COc1ccc(C2COCCOC2)c2sc(NC(=O)c3ccc(CCl)cc3)nc12
HCID11750844

未命名化合物

结构：COc1ccc(-c2ccccc2)c2sc(NC(=O)c3ccc(CN4CCCC4)cc3)nc12
HCID22283140

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(C2COCCOC2)c2sc(NC(=O)c3ccc(CN4CCCC4)cc3)nc12
HCID86595145

未命名化合物

PROCEDURE

实验过程

4-Chloromethyl-N-(7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-yl)-benzamide and pyrrolidine were reacted as described for N-(4-methoxy-7-phenyl-benzothiazol-2-yl)-4-pyrrolidin-1-ylmethyl-benzamide in WO01/9786. Usual workup, preparative reversed-phase HPLC and final dry-freezing afforded the title compound as light brown powder. MS: m/e=468(M+H+).

WORKUP

后处理

  1. customUsual workup, preparative reversed-phase HPLC and final dry-freezing