Pyruvic Acid → HCID 67852619, compound

HRID 2226395Notes

Reaction equation

[NH2:1][C@H:2]([C:4]([N:6]1[CH:14]2[CH:9]([CH2:10][CH2:11][CH2:12][CH2:13]2)[CH2:8][C@H:7]1[C:15]([OH:17])=[O:16])=[O:5])[CH3:3].[C:18]([OH:23])(=[O:22])[C:19]([CH3:21])=O.C([BH3-])#N.[Na+]>>[C:18]([CH:19]([NH:1][C@H:2]([C:4]([N:6]1[CH:14]2[CH:9]([CH2:10][CH2:11][CH2:12][CH2:13]2)[CH2:8][C@H:7]1[C:15]([OH:17])=[O:16])=[O:5])[CH3:3])[CH3:21])([OH:23])=[O:22]

Participants

Reactant 3

HCID 1060Pyruvic Acid

HCID 5003444Sodium cyanoborohydride

HCID 13146116HCID 13146116, compound

Product 1

HCID 67852619HCID 67852619, compound

Procedure

As described in Example 5, react 1 -[(S)-alanyl ]octahydroindole-2(S)-carboxylic acid (prepared as described in Example 1) and pyruvic acid with sodium cyanoborohydride to obtain the title compound.

Sources & evidence

ORD record: ord-f2d725c801884887a8dd335d97e68d46
Source dataset: uspto-grants-1994_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05348944

Reaction notes

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