Water → HCID 23297209, compound

HRID 2226567Notes

Reaction equation

HRID 2226567 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10](=O)[CH3:11])[CH:5]=[CH:6][C:7]=1[Cl:8].[C-]#N.[K+].[C:16](=[O:19])(O)O.[NH4+:20].[C:21](=[O:24])([O-])[O-].C(=O)(O)O.[NH4+:29].O>C(O)C>[Cl:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][C:7]=1[Cl:8])[CH2:9][C:10]1([CH3:11])[NH:29][C:21](=[O:24])[NH:20][C:16]1=[O:19]

Participants

6

Reactant 4

HCID 962WaterHCID 9032Potassium CyanideHCID 810603',4'-DichloropropiophenoneHCID 131718677HCID 131718677, compound

Product 1

HCID 23297209HCID 23297209, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
40 °C

Procedure

160.0 g (0.79 mol) of 3,4-dichlorophenylacetone in 700 ml of ethanol are introduced into a reactor, and the mixture is heated to 40° C. to obtain dissolution. 53.0 g (0.81 mol) of potassium cyanide, 149.0 g of ammonium sesquicarbonate and 700 ml of water are then added.

Workup

  1. customto obtain
  2. dissolutiondissolution

Sources & evidence

ORD record
ord-128ac51ad6684f60802f73828b351f47
Source dataset
uspto-grants-1994_09
Patent number
US05348980

Reaction notes

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