2-Phenylethanol → HCID 18471977, compound

HRID 2227131Notes

Reaction equation

HRID 2227131 reaction equation
[C:1]1([CH2:7][CH2:8][OH:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:10]=[CH:11][C:12]1[CH:17]=[CH:16][C:15]([S:18](Cl)(=[O:20])=[O:19])=[CH:14][CH:13]=1.C(N(CC)CC)C>ClCCl>[CH2:10]=[CH:11][C:12]1[CH:13]=[CH:14][C:15]([S:18]([O:9][CH2:8][CH2:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)(=[O:20])=[O:19])=[CH:16][CH:17]=1

Participants

5

Reactant 3

HCID 60542-PhenylethanolHCID 8471TriethylamineHCID 9855777Styrene-4-sulfonyl chloride

Product 1

HCID 18471977HCID 18471977, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2-Phenylethanol (3.1 g) was reacted with p-styrene sulfonyl chloride (5.3 g) and triethylamine (2.7 g) in 20 ml of dichloromethane for 3 hours to give the desired product as a light yellow viscous oil that was purified by passing through basic aluminum oxide.

Sources & evidence

ORD record
ord-874be716e65d480aa5a1a5e256a07d9a
Source dataset
uspto-grants-2002_07
Patent number
US06413694B1

Reaction notes

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