Tryptamine → HCID 86758299, compound

HRID 2227289Notes

Reaction equation

HRID 2227289 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4](Cl)[N:3]=1.NCC[C:20]1[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[NH:22][CH:21]=1.[CH2:29]([N:31](CC)CC)[CH3:30]>>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4]([N:31]([C:20]2[C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[NH:22][CH:21]=2)[CH2:29][CH3:30])[N:3]=1

Participants

4

Reactant 3

HCID 1150TryptamineHCID 8471TriethylamineHCID 108011162,6-dichloro-9-cyclopentyl-9H-purine

Product 1

HCID 86758299HCID 86758299, compound

Procedure

2-Chloro-6-[(3-indolyl)-2-ethylamino]-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, tryptamine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Sources & evidence

ORD record
ord-c238a71ffd254e638371bab0d9adf5a6
Source dataset
uspto-grants-2002_07
Patent number
US06413974B1

Reaction notes

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