2-Morpholinoethylamine → HCID 18473374, compound

HRID 2227300Notes

Reaction equation

HRID 2227300 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4](Cl)[N:3]=1.[NH2:17][CH2:18][CH2:19][N:20]1[CH2:25][CH2:24][O:23][CH2:22][CH2:21]1>C(N(CC)CC)C>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4]([NH:17][CH2:18][CH2:19][N:20]2[CH2:25][CH2:24][O:23][CH2:22][CH2:21]2)[N:3]=1

Participants

4

Reactant 2

HCID 4082852-MorpholinoethylamineHCID 108011162,6-dichloro-9-cyclopentyl-9H-purine

Product 1

HCID 18473374HCID 18473374, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Chloro-6-[2-(4-morpholinyl)ethylamino]-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, 2-aminoethylmorpholine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Sources & evidence

ORD record
ord-56f4db6a892e4427866c6bcdf34dc1c0
Source dataset
uspto-grants-2002_07
Patent number
US06413974B1

Reaction notes

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