Hydrochloric Acid → HCID 13369493, compound

HRID 2231142Notes

Reaction equation

HRID 2231142 reaction equation
[CH:1]([NH:4][C:5](=O)[CH:6]([Cl:8])[Cl:7])([CH3:3])[CH3:2].Cl.P(Cl)(Cl)([Cl:13])=O>P(Cl)(Cl)(Cl)(Cl)Cl>[CH:1]([N:4]=[C:5]([Cl:13])[CH:6]([Cl:8])[Cl:7])([CH3:3])[CH3:2]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 24813Phosphorus oxychlorideHCID 3550524HCID 3550524, compound

Product 1

HCID 13369493HCID 13369493, compoundYield 65%

Reagents, catalysts & solvents 1

HCID 24819Phosphorus pentachlorideSolvent

Procedure

N-isopropyldichloroacetamide, 249.5 grams (2.94 mole), and 210 milliliters of phosphorous pentachloride, 306.5 grams (2.94 mole), was added and the mixture was stirred vigorously and heated at reflux until hydrogen chloride evolution ceased. The phosphorous oxychloride was stripped off at reduced pressure. Distillation at 4.5 millimeters gave 360 grams (65% yield) of N-isopropyldichloroacetimidoyl chloride, b.p. 63°-72° C.

Workup

  1. temperatureheated
  2. distillationDistillation at 4.5 millimeters

Sources & evidence

ORD record
ord-9db961b84c6e481fb7b16461420c6773
Source dataset
uspto-grants-1988_11
Patent number
US04781752

Reaction notes

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