Selenium Dioxide → 1-Methyl-1H-imidazo(4,5-c)pyridine-2-carboxaldehyde

HRID 2231259Notes

Reaction equation

HRID 2231259 reaction equation
[CH3:1][N:2]1[C:10]2[CH:9]=[CH:8][N:7]=[CH:6][C:5]=2[N:4]=[C:3]1[CH3:11].[Se](=O)=[O:13]>O1CCOCC1>[CH3:1][N:2]1[C:10]2[CH:9]=[CH:8][N:7]=[CH:6][C:5]=2[N:4]=[C:3]1[CH:11]=[O:13]

Participants

4

Reactant 2

HCID 24007Selenium DioxideHCID 42873941,2-Dimethyl-1H-imidazo[4,5-c]pyridine

Product 1

HCID 122393311-Methyl-1H-imidazo(4,5-c)pyridine-2-carboxaldehydeYield 80.1%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Using the procedure of Example 10B and starting with 357 mg of 1,2-dimethyl-1H-imidazo[4,5-c]pyridine and 270 mg of selenium dioxide in 30 ml of dioxane, there was obtained 313 mg of the title product.

Sources & evidence

ORD record
ord-f16a98ce42e14e278be59bca28dae01a
Source dataset
uspto-grants-1988_11
Patent number
US04782050

Reaction notes

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