Hydrochloric Acid → HCID 21284872, compound

HRID 2231874Notes

Reaction equation

HRID 2231874 reaction equation
[C:1]1(=[O:19])[N:5]([CH2:6][C:7](=O)[CH2:8][CH2:9][C:10](=O)[CH3:11])[C:4](=[O:14])[C:3]2=[CH:15][CH:16]=[CH:17][CH:18]=[C:2]12.[N:20]1([CH2:25][CH2:26][CH2:27][NH2:28])[CH:24]=[CH:23][N:22]=[CH:21]1.[ClH:29]>C(O)(=O)C>[ClH:29].[N:20]1([CH2:25][CH2:26][CH2:27][N:28]2[C:10]([CH3:11])=[CH:9][CH:8]=[C:7]2[CH2:6][N:5]2[C:4](=[O:14])[C:3]3=[CH:15][CH:16]=[CH:17][CH:18]=[C:2]3[C:1]2=[O:19])[CH:24]=[CH:23][N:22]=[CH:21]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 787361H-Imidazole-1-propanamineHCID 123484512-(2,5-Dioxohexyl)-1H-isoindole-1,3(2H)-dione

Product 1

HCID 21284872HCID 21284872, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

5.2 g (0.02 mol) of 6-phthalimido-2,5-hexanedione and 2.5 g (0.02 mol) of 3-(1-imidazolyl)-propylamine are stirred in 70 ml of acetic acid at 80° C. for 2 hours and the mixture is worked up as in Example 1. After ethanolic hydrochloric acid has been added, the product is filtered off and recrystallised from ethanol.

Workup

  1. filtrationthe product is filtered off
  2. customrecrystallised from ethanol

Sources & evidence

ORD record
ord-efdaa5cb6e5b4c979265bfeeb3b3bbaf
Source dataset
uspto-grants-1988_11
Patent number
US04785010

Reaction notes

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