m-Chloroperbenzoic acid → 6-(Ethanesulfinyl)-3-phenyl[1,2,4]triazolo[3,4-a]phthalazine

HRID 2232226Notes

Reaction equation

HRID 2232226 reaction equation
ClC1C=CC=C(C(OO)=[O:9])C=1.[CH2:12]([S:14][C:15]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[C:18]2=[N:25][N:26]=[C:27]([C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)[N:17]2[N:16]=1)[CH3:13]>C(Cl)Cl>[CH2:12]([S:14]([C:15]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[C:18]2=[N:25][N:26]=[C:27]([C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)[N:17]2[N:16]=1)=[O:9])[CH3:13]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 30712341,2,4-Triazolo(3,4-a)phthalazine, 6-(ethylthio)-3-phenyl-

Product 1

HCID 30712366-(Ethanesulfinyl)-3-phenyl[1,2,4]triazolo[3,4-a]phthalazine

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

m-Chloroperbenzoic acid (3.1 g) is added to a solution of the compound of example 109 (4.6 g) in methylene chloride (50 ml) and the reaction mixture is stirred at room temperature for five hours. The mixture is washed first with diluted sodium metabisulfite and then with aqueous sodium bicarbonate.

Workup

  1. washThe mixture is washed first with diluted sodium metabisulfite

Sources & evidence

ORD record
ord-bc4c342138454f5c91c33c9ac57f73ea
Source dataset
uspto-grants-1988_11
Patent number
US04788186

Reaction notes

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