反应详情

温度

100 °C

A mixture of 3,8-dichloro-6-phenyl-1,2,4-triazolo[3,4-a]phthalazine (5 g), sodium ethoxide (1.3 g) and absolute ethanol (40 ml) is poured into a steel bomb and heated to 100° C. for 8 hours. Then the mixture is cooled and concentrated to dryness. The obtained residue is triturated with water, filtered and crystallized from ethanol/chloroform yielding 3.3 g of the compound of the title. M.p. 226°-28° C.

1. temperatureThen the mixture is cooled
2. concentrationconcentrated to dryness
3. customThe obtained residue is triturated with water
4. filtrationfiltered
5. customcrystallized from ethanol/chloroform yielding 3.3 g of the compound of the title