Piperidine → HCID 20553715, compound

HRID 223246Notes

Reaction equation

HRID 223246 reaction equation
[CH3:1][C:2]1([CH2:16][O:17][CH2:18][CH2:19]O)[C:7]2[CH:8]=[C:9]([O:14][CH3:15])[C:10]([O:12][CH3:13])=[CH:11][C:6]=2[CH2:5][CH2:4][S:3]1.[N+:21]([C:24]1C=[CH:28][C:27](S([O-])(=O)=O)=[CH:26][CH:25]=1)([O-])=O.N1CCCCC1>C1COCC1>[CH3:1][C:2]1([CH2:16][O:17][CH2:18][CH2:19][N:21]2[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]2)[C:7]2[CH:8]=[C:9]([O:14][CH3:15])[C:10]([O:12][CH3:13])=[CH:11][C:6]=2[CH2:5][CH2:4][S:3]1

Participants

4

Reactant 2

HCID 8082PiperidineHCID 86736523HCID 86736523, compound

Product 1

HCID 20553715HCID 20553715, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A mixture of 2-[[1-methyl-6,7-dimethoxy-3,4-dihydro-1H-2-benzothiopyran-1-yl]methoxy]ethanol-4-nitrobenzenesulfonate and piperidine is stirred at room temperature in THF. The mixture is then partitioned between methylene chloride and aqueous sodium carbonate. The title compound is isolated by chromatography and is crystallized.

Workup

  1. customThe mixture is then partitioned between methylene chloride and aqueous sodium carbonate

Sources & evidence

ORD record
ord-48c27a8ee05b4f288fa4488dc458b009
Source dataset
uspto-grants-1982_10
Patent number
US04352805

Reaction notes

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