Hydrochloric Acid → 4-Methylbenzo[d]thiazol-2-ol

HRID 223399Notes

Reaction equation

HRID 223399 reaction equation
C([O:3][C:4]1[S:5][C:6]2[CH:12]=[CH:11][CH:10]=[C:9]([CH3:13])[C:7]=2[N:8]=1)C.Cl>C1(C)C(C)=CC=CC=1>[CH3:13][C:9]1[C:7]2[NH:8][C:4](=[O:3])[S:5][C:6]=2[CH:12]=[CH:11][CH:10]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 20522292HCID 20522292, compound

Product 1

HCID 127708804-Methylbenzo[d]thiazol-2-olYield 81%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

Prepared analogous to Example 5 from 2-ethoxy-4-methyl-benzothiazole and concentrated hydrochloric acid with a yield of 81% of theory. M.p.: 207°-208° C. (xylene/gasoline 1:1)

Sources & evidence

ORD record
ord-fd21514664d84b5db156de43cf24b9c9
Source dataset
uspto-grants-1982_10
Patent number
US04353919

Reaction notes

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